{"id":256,"date":"2025-04-25T13:46:16","date_gmt":"2025-04-25T13:46:16","guid":{"rendered":"https:\/\/dcv-berger-allemand.fr\/?page_id=256"},"modified":"2025-07-18T09:43:17","modified_gmt":"2025-07-18T09:43:17","slug":"maladies","status":"publish","type":"page","link":"https:\/\/dcv-berger-allemand.fr\/en\/sante\/maladies\/","title":{"rendered":"Genetic diseases detected in German Shepherds"},"content":{"rendered":"
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\"Maladies
DNA<\/figcaption><\/figure>\n

Recent scientific discoveries make it possible to determine whether a dog is disease-free, a healthy carrier, or affected by a disease, based on the presence or absence of a specific mutation on one or two alleles of the gene concerned.<\/p>\n

This is why the Central Canine Society (SCC)<\/a>, in conjunction with breed clubs, recommends screening for certain hereditary diseases in breeders.<\/p>\n

Here are the conditions tested:<\/strong><\/p>\n<\/div>\n<\/div>\n<\/div>\n

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\u2022 Degenerative myelopathy type A (DM): neurological disease affecting the spinal cord, transmitted by mutation of the SOD1 gene.<\/p>\n

\u2022 Hyperuricosuria (HUU): metabolic disease predisposing to urinary stones.<\/p>\n

\u2022 X-linked ectodermal dysplasia (XHED): a disease affecting the skin and coat, with specific sex-linked inheritance.<\/p>\n

\u2022 Rare disorders under surveillance such as mucopolysaccharidosis VII, hemophilia A or Scott syndrome.<\/p>\n

\u2013 MPS-VII (mucopolysaccharidosis VII): a rare genetic disease affecting metabolism, leading to the accumulation of complex sugars in cells, causing skeletal, cardiac and neurological disorders in dogs.<\/p>\n

\u2013 HEMA-1 and HEMA-2 (hemophilia A): inherited blood clotting disorders linked to the X chromosome, causing prolonged bleeding even after minor injuries.<\/p>\n

\u2013 CSS (Scott syndrome): genetic disease of the immune system characterized by an abnormality in platelet adhesion, leading to coagulation disorders similar to those observed in hemophilia.<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Impact on reproduction<\/strong><\/h3>\n

A dog's genetic status has important consequences on mating choices:<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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\u2022 An unaffected dog can be bred without restriction- 1.1 or NN.<\/strong>
\n\u2022 A healthy carrier dog (heterozygous for a recessive mutation) can be bred, but only with an unaffected dog to avoid producing diseased puppies. 1.2 or NM<\/strong>
\n\u2022 An affected dog (homozygous mutated) should not be used for breeding as part of a responsible selection policy. \u2013 2.2 or MM<\/strong><\/p>\n

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\"Transmission<\/p>\n

Transmission of genetic diseases to offspring through mating<\/p>\n

This system allows for the gradual elimination of deleterious mutations while preserving the genetic diversity of breeds.<\/strong><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n

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\nContinue to the next section
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\u00a9 2025 \u00c9levage des Crocs V\u00e9ritables<\/span><\/div>\n

 <\/p>\n

Quick navigation:<\/strong><\/div>\n
Home<\/a>
\nThe German Shepherd<\/a> | Health<\/a> | Selection<\/a> | Living with a German Shepherd<\/a> | Education and training<\/a> | Breeding<\/a> | Photos<\/a> | Contact<\/a> | Links <\/a> | Articles and Reflections<\/a><\/span><\/em><\/div>","protected":false},"excerpt":{"rendered":"

Les re\u0301centes de\u0301couvertes scientifiques permettent de de\u0301terminer si un chien est indemne, porteur sain ou atteint d\u2019une maladie, en fonction de la pre\u0301sence ou non d\u2019une mutation spe\u0301cifique sur un ou deux alle\u0300les du ge\u0300ne concerne\u0301. C\u2019est pourquoi la Socie\u0301te\u0301 Centrale Canine (SCC), en lien avec les clubs de race, recommande le de\u0301pistage de certaines […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":139,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-256","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/pages\/256","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/comments?post=256"}],"version-history":[{"count":17,"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/pages\/256\/revisions"}],"predecessor-version":[{"id":1402,"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/pages\/256\/revisions\/1402"}],"up":[{"embeddable":true,"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/pages\/139"}],"wp:attachment":[{"href":"https:\/\/dcv-berger-allemand.fr\/en\/wp-json\/wp\/v2\/media?parent=256"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}